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Bioluminescent Antibodies for Point‐of‐Care Diagnostics
We introduce a general method to transform antibodies into ratiometric, bioluminescent sensor proteins for the no‐wash quantification of analytes. Our approach is based on the genetic fusion of antibody fragments to NanoLuc luciferase and SNAP‐tag, the latter being labeled with a synthetic fluoresce...
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| Publicat a: | Angew Chem Int Ed Engl |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488172/ https://ncbi.nlm.nih.gov/pubmed/28510347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201702403 |
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