Extracellular renalase protects cells and organs by outside‐in signalling

Renalase was discovered as a protein synthesized by the kidney and secreted in blood where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested that it functioned as an NAD(P)H oxidase and could oxidize catecholamines. Administration of renalase lowers blood pressur...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Wang, Yang, Safirstein, Robert, Velazquez, Heino, Guo, Xiao‐Jia, Hollander, Lindsay, Chang, John, Chen, Tian‐Min, Mu, Jian‐Jun, Desir, Gary V.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487909/
https://ncbi.nlm.nih.gov/pubmed/28238213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13062
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