A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed. After heat shock, to which sexual but not asexual spores are highly resistant, the azole-free compost yielded 98% (49/50) wild...

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Vydáno v:mBio
Hlavní autoři: Zhang, Jianhua, Snelders, Eveline, Zwaan, Bas J., Schoustra, Sijmen E., Meis, Jacques F., van Dijk, Karin, Hagen, Ferry, van der Beek, Martha T., Kampinga, Greetje A., Zoll, Jan, Melchers, Willem J. G., Verweij, Paul E., Debets, Alfons J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487732/
https://ncbi.nlm.nih.gov/pubmed/28655821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00791-17
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