Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes

AIMS/HYPOTHESIS: Pancreatic lymph nodes (PLNs) are critical sites for the initial interaction between islet autoantigens and autoreactive lymphocytes, but the histology of PLNs in tissue from individuals with type 1 diabetes has not been analysed in detail. The aim of this study was to examine PLN t...

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Bibliographic Details
Published in:Diabetologia
Main Authors: Willcox, Abby, Richardson, Sarah J., Walker, Lucy S. K., Kent, Sally C., Morgan, Noel G., Gillespie, Kathleen M.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487689/
https://ncbi.nlm.nih.gov/pubmed/28213757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4221-7
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