In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine, and MIV-150, Nonnucleoside Reverse Transcriptase Inhibitor Microbicides in Clinical Development for the Prevention of HIV-1 Infection

Rilpivirine (RPV), dapivirine (DPV), and MIV-150 are in development as microbicides. It is not known whether they will block infection of circulating nonnucleoside reverse transcriptase inhibitor (NNRTI)-resistant human immunodeficiency virus type 1 (HIV-1) variants. Here, we demonstrate that the ac...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Giacobbi, Nicholas S., Sluis-Cremer, Nicolas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487620/
https://ncbi.nlm.nih.gov/pubmed/28507107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00277-17
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