Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE’s STAT-Net

PURPOSE: In this era of rising antimicrobial resistance, slowly refilling antibiotic development pipelines, and an aging population, we need to ensure that randomized clinical trials (RCTs) determine the added benefit of new antibiotic agents effectively and in a valid way, especially for severely i...

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Detalhes bibliográficos
Publicado no:Intensive Care Med
Main Authors: Timsit, Jean-François, de Kraker, Marlieke E. A., Sommer, Harriet, Weiss, Emmanuel, Bettiol, Esther, Wolkewitz, Martin, Nikolakopoulos, Stavros, Wilson, David, Harbarth, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487537/
https://ncbi.nlm.nih.gov/pubmed/28466147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-017-4802-4
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