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A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects

Rationale: Renewed interest has been seen in the use of lysergic acid diethylamide (LSD) in psychiatric research and practice. The repeated use of LSD leads to tolerance that is believed to result from serotonin (5-HT) 5-HT(2A) receptor downregulation. In rats, daily LSD administration for 4 days de...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Dolder, Patrick C., Grünblatt, Edna, Müller, Felix, Borgwardt, Stefan J., Liechti, Matthias E.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487530/
https://ncbi.nlm.nih.gov/pubmed/28701958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00423
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