Cerebrospinal Fluid Aβ43 Is Reduced in Early-Onset Compared to Late-Onset Alzheimer’s Disease, But Has Similar Diagnostic Accuracy to Aβ42

Background: Amyloid beta 1–43 (Aβ43) may be a useful additional biomarker for diagnosing Alzheimer’s disease (AD). We have investigated cerebrospinal fluid (CSF) levels of Aβ43 in patients with early-onset AD in contrast to levels in late-onset AD. For comparison, in addition to the ‘core’ biomarker...

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Vydáno v:Front Aging Neurosci
Hlavní autoři: Lauridsen, Camilla, Sando, Sigrid B., Møller, Ina, Berge, Guro, Pomary, Precious K., Grøntvedt, Gøril R., Salvesen, Øyvind, Bråthen, Geir, White, Linda R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487529/
https://ncbi.nlm.nih.gov/pubmed/28701950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00210
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