Glutamatergic deficit and schizophrenia-like negative symptoms: new evidence from ketamine-induced mismatch negativity alterations in healthy male humans

BACKGROUND: Targeting the N-methyl-d-aspartate receptor (NMDAR) is a major translational approach for treating negative symptoms of schizophrenia. Ketamine comprehensively produces schizophrenia-like symptoms, such as positive, cognitive and negative symptoms in healthy volunteers. The amplitude of...

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Veröffentlicht in:J Psychiatry Neurosci
Hauptverfasser: Thiebes, Stephanie, Leicht, Gregor, Curic, Stjepan, Steinmann, Saskia, Polomac, Nenad, Andreou, Christina, Eichler, Iris, Eichler, Lars, Zöllner, Christian, Gallinat, Jürgen, Hanganu-Opatz, Ileana, Mulert, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Joule Inc. 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487274/
https://ncbi.nlm.nih.gov/pubmed/28556775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.160187
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