The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors

BACKGROUND AND AIM: Desmoplasia is a characteristic feature and a suspected mechanism of tumor progression in pancreatic ductal adenocarcinoma (PDAC). Main constituents of the stroma involve cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM). The aim of this study was to dissect the...

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Publicado en:Transl Oncol
Autores principales: Bolm, Louisa, Cigolla, Simon, Wittel, Uwe A., Hopt, Ulrich T., Keck, Tobias, Rades, Dirk, Bronsert, Peter, Wellner, Ulrich Friedrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2017
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487255/
https://ncbi.nlm.nih.gov/pubmed/28658650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.04.009
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