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Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway

The intestinal epithelial barrier, composed of epithelial cells, tight junction proteins and intestinal secretions, prevents passage of luminal substances and antigens through the paracellular space. Dysfunction of the intestinal barrier integrity induced by toxins and pathogens is associated with a...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Yan, Hui, Ajuwon, Kolapo M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487041/
https://ncbi.nlm.nih.gov/pubmed/28654658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179586
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