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Dual role of α-defensin-1 in anti–HIV-1 innate immunity

α-Defensins are abundant antimicrobial peptides in polymorphonuclear leukocytes and play an important role in innate immunity. We have previously shown that α-defensin-1 can inhibit HIV-1 replication following viral entry. Here we examined the molecular mechanism(s) of α-defensin-1–mediated HIV-1 in...

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Detalhes bibliográficos
Main Authors: Chang, Theresa L., Vargas, Jesus, DelPortillo, Armando, Klotman, Mary E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548697/
https://ncbi.nlm.nih.gov/pubmed/15719067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200521948
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