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Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start?

It is well recognised that a state of autoimmunity, in which immunological tolerance is broken, precedes the development of symptoms in the majority of patients with rheumatoid arthritis (RA). For individuals who will later develop seropositive disease, this manifests as autoantibodies directed agai...

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Detalhes bibliográficos
Publicado no:Semin Immunopathol
Main Authors: Tracy, Alexander, Buckley, Christopher D., Raza, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486797/
https://ncbi.nlm.nih.gov/pubmed/28337522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-017-0620-6
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