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Penetration and distribution of gadolinium-based contrast agents into the cerebrospinal fluid in healthy rats: a potential pathway of entry into the brain tissue

OBJECTIVE: Signal hyperintensity on unenhanced MRI in certain brain regions has been reported after multiple administrations of some, but not all, gadolinium-based contrast agents (GBCAs). One potential initial pathway of GBCA entry into the brain, infiltration from blood into the cerebrospinal flui...

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Publicat a:Eur Radiol
Autors principals: Jost, Gregor, Frenzel, Thomas, Lohrke, Jessica, Lenhard, Diana Constanze, Naganawa, Shinji, Pietsch, Hubertus
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486780/
https://ncbi.nlm.nih.gov/pubmed/27832312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00330-016-4654-2
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