Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets of injury. Metals are essential for normal CNS functioning, and metal imbalances have been...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Popescu, Bogdan F., Frischer, Josa M., Webb, Samuel M., Tham, Mylyne, Adiele, Reginald C., Robinson, Christopher A., Fitz-Gibbon, Patrick D., Weigand, Stephen D., Metz, Imke, Nehzati, Susan, George, Graham N., Pickering, Ingrid J., Brück, Wolfgang, Hametner, Simon, Lassmann, Hans, Parisi, Joseph E., Yong, Guo, Lucchinetti, Claudia F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486634/
https://ncbi.nlm.nih.gov/pubmed/28332093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1696-8
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