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The splenic marginal zone shapes the phenotype of leukemia B cells and facilitates their niche-specific retention and survival
Microenvironmental regulation in lymphoid tissues is essential for the development of chronic lymphocytic leukemia. We identified cellular and molecular factors provided by the splenic marginal zone (MZ), which alter the migratory and adhesive behavior of leukemic cells. We used the Cxcr5(−/−)Eµ-Tcl...
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| Publicado no: | Oncoimmunology |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5486190/ https://ncbi.nlm.nih.gov/pubmed/28680761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1323155 |
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