CD39/CD73 upregulation on myeloid-derived suppressor cells via TGF-β-mTOR-HIF-1 signaling in patients with non-small cell lung cancer

CD39/CD73-adenosine pathway has been recently defined as an important tumor-induced immunosuppressive mechanism. We here documented a fraction of CD11b(+)CD33(+) myeloid-derived suppressor cells (MDSCs) in peripheral blood and tumor tissues from non-small cell lung cancer (NSCLC) patients expressed...

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Publicat a:Oncoimmunology
Autors principals: Li, Jieyao, Wang, Liping, Chen, Xinfeng, Li, Lifeng, Li, Yu, Ping, Yu, Huang, Lan, Yue, Dongli, Zhang, Zhen, Wang, Fei, Li, Feng, Yang, Li, Huang, Jianmin, Yang, Shuangning, Li, Hong, Zhao, Xuan, Dong, Wenjie, Yan, Yan, Zhao, Song, Huang, Bo, Zhang, Bin, Zhang, Yi
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486179/
https://ncbi.nlm.nih.gov/pubmed/28680754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320011
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