Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis

Granulosa cells are crucial for follicular growth, development, and follicular atresia. X-box binding protein 1 (XBP1), a basic region-leucine zipper protein, is widely involved in cell differentiation, proliferation, apoptosis, cellular stress response, and other signaling pathways. In this study,...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Wang, Nan, Zhao, Fan, Lin, Pengfei, Zhang, Guangle, Tang, Keqiong, Wang, Aihua, Jin, Yaping
Format: Artigo
Language:Inglês
Published: MDPI 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485976/
https://ncbi.nlm.nih.gov/pubmed/28555054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18061152
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