Systematic discovery of novel eukaryotic transcriptional regulators using sequence homology independent prediction

BACKGROUND: The molecular function of a gene is most commonly inferred by sequence similarity. Therefore, genes that lack sufficient sequence similarity to characterized genes (such as certain classes of transcriptional regulators) are difficult to classify using most function prediction algorithms...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Bossi, Flavia, Fan, Jue, Xiao, Jun, Chandra, Lilyana, Shen, Max, Dorone, Yanniv, Wagner, Doris, Rhee, Seung Y.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485742/
https://ncbi.nlm.nih.gov/pubmed/28651538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3853-9
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