Evidence for an early innate immune response in the motor cortex of ALS

BACKGROUND: Recent evidence indicates the importance of innate immunity and neuroinflammation with microgliosis in amyotrophic lateral sclerosis (ALS) pathology. The MCP1 (monocyte chemoattractant protein-1) and CCR2 (CC chemokine receptor 2) signaling system has been strongly associated with the in...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Jara, Javier H., Genç, Barış, Stanford, Macdonell J., Pytel, Peter, Roos, Raymond P., Weintraub, Sandra, Mesulam, M. Marsel, Bigio, Eileen H., Miller, Richard J., Özdinler, P. Hande
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485686/
https://ncbi.nlm.nih.gov/pubmed/28651542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0896-4
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