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Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution

Aquaporin (AQP) 6 belongs to the aquaporin water channel family. Unlike other aquaporins, AQP6 functions not as a water channel but as an anion-selective channel. Single-channel analyses have shown AQP6 to flicker rapidly between closed and open status. The atomic structure of AQP1 and amino acid se...

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Autors principals: Liu, Kun, Kozono, David, Kato, Yasuhiro, Agre, Peter, Hazama, Akihiro, Yasui, Masato
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548568/
https://ncbi.nlm.nih.gov/pubmed/15671159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409232102
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