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The CD4+ T cell regulatory network mediates inflammatory responses during acute hyperinsulinemia: a simulation study

BACKGROUND: Obesity is frequently linked to insulin resistance, high insulin levels, chronic inflammation, and alterations in the behaviour of CD4+ T cells. Despite the biomedical importance of this condition, the system-level mechanisms that alter CD4+ T cell differentiation and plasticity are not...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Martinez-Sanchez, Mariana E., Hiriart, Marcia, Alvarez-Buylla, Elena R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485658/
https://ncbi.nlm.nih.gov/pubmed/28651594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0436-y
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