A novel TRPM8 agonist relieves dry eye discomfort

BACKGROUND: Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activate...

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Dettagli Bibliografici
Pubblicato in:BMC Ophthalmol
Autori principali: Yang, Jee Myung, Li, Fengxian, Liu, Qin, Rüedi, Marco, Wei, Edward Tak, Lentsman, Michael, Lee, Hyo Seok, Choi, Won, Kim, Seong Jin, Yoon, Kyung Chul
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485613/
https://ncbi.nlm.nih.gov/pubmed/28651550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-017-0495-2
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