High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report

OBJECTIVE: Advanced glycation end products (AGEs) are important in the pathophysiology of type 2 diabetes mellitus (T2DM). They directly cause insulin secretory defects in animal and cell culture models and may promote insulin resistance in nondiabetic subjects. We have developed a highly sensitive...

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Publié dans:J Diabetes Res
Auteurs principaux: Okura, Tsuyoshi, Ueta, Etsuko, Nakamura, Risa, Fujioka, Yohei, Sumi, Keisuke, Matsumoto, Kazuhisa, Shoji, Kyoko, Matsuzawa, Kazuhiko, Izawa, Shoichiro, Nomi, Yuri, Mihara, Hitomi, Otsuka, Yuzuru, Kato, Masahiko, Taniguchi, Shin-ichi, Yamamoto, Kazuhiro
Format: Artigo
Langue:Inglês
Publié: Hindawi 2017
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485485/
https://ncbi.nlm.nih.gov/pubmed/28695132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5139750
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