Parkin Knockout Inhibits Neuronal Development via Regulation of Proteasomal Degradation of p21

PARK2 encodes for the E3 ubiquitin ligase parkin and is implicated in the development of Parkinson's disease (PD). Although the neuroprotective role of parkin is well known, the mechanism of PARK2's function in neural stem differentiation has not yet been thoroughly studied. Co-expressions...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Park, Mi Hee, Lee, Hwa-Jeong, Lee, Hye Lim, Son, Dong Ju, Ju, Jung Hoon, Hyun, Byung Kook, Jung, Sung Hee, Song, Ju-Kyoung, Lee, Dong Hun, Hwang, Chul Ju, Han, Sang Bae, Kim, Sanghyeon, Hong, Jin Tae
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485421/
https://ncbi.nlm.nih.gov/pubmed/28656059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19824
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