WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells

Mutations in WD40-repeat protein 62 (WDR62) are commonly associated with primary microcephaly and other developmental cortical malformations. We used human pluripotent stem cells (hPSC) to examine WDR62 function during human neural differentiation and model early stages of human corticogenesis. Neur...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Alshawaf, Abdullah J., Antonic, Ana, Skafidas, Efstratios, Ng, Dominic Chi-Hung, Dottori, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485354/
https://ncbi.nlm.nih.gov/pubmed/28690640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7848932
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