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Accelerated Hantzsch electrospray synthesis with temporal control of reaction intermediates

Complex chemical reactions can occur in electrosprayed droplets on the millisecond time scale. The Hantzsch synthesis of 1,4-dihydropyridines was studied in this way using on-line mass spectral analysis to optimize conditions and characterize the product mixture. Changing the distance between the na...

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Publicat a:Chem Sci
Autors principals: Bain, Ryan M., Pulliam, Christopher J., Cooks, R. Graham
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485237/
https://ncbi.nlm.nih.gov/pubmed/28694938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02436b
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