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Generation of human antibody fragments against Streptococcus mutans using a phage display chain shuffling approach

BACKGROUND: Common oral diseases and dental caries can be prevented effectively by passive immunization. In humans, passive immunotherapy may require the use of humanized or human antibodies to prevent adverse immune responses against murine epitopes. Therefore we generated human single chain and di...

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Detalhes bibliográficos
Main Authors: Kupper, Michael B, Huhn, Michael, Spiegel, Holger, Ma, Julian KC, Barth, Stefan, Fischer, Rainer, Finnern, Ricarda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548521/
https://ncbi.nlm.nih.gov/pubmed/15667665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-4
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