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Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice

BACKGROUND: In Leber's congenital amaurosis (LCA), affected individuals are blind, or nearly so, from birth. This early onset suggests abnormal development of the neural retina. Mutations in genes that affect the development and/or function of photoreceptor cells have been found to be responsib...

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Autori principali: Morrow, Eric M, Furukawa, Takahisa, Raviola, Elio, Cepko, Constance L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC548520/
https://ncbi.nlm.nih.gov/pubmed/15676071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-6-5
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