Aberrant splicing of androgen receptor mRNA results in synthesis of a nonfunctional receptor protein in a patient with androgen insensitivity.

Androgen insensitivity is a disorder in which the correct androgen response in an androgen target cell is impaired. The clinical symptoms of this X chromosome-linked syndrome are presumed to be caused by mutations in the androgen receptor gene. We report a G----T mutation in the splice donor site of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ris-Stalpers, C, Kuiper, G G, Faber, P W, Schweikert, H U, van Rooij, H C, Zegers, N D, Hodgins, M B, Degenhart, H J, Trapman, J, Brinkmann, A O
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2236003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.20.7866
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