Role of miR‐155 in the regulation of MMP‐16 expression in intervertebral disc degeneration

The molecular mechanisms of intervertebral disc degeneration (IDD) remain elusive. We found that miR‐155 is down‐regulated in degenerative nucleus pulposus (NP), and more severe degeneration is correlated with higher matrix metallopeptidase 16 (MMP‐16) expression. MMP‐16 also degraded matrix aggreca...

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Bibliografiske detaljer
Udgivet i:J Orthop Res
Main Authors: Zhang, Wei‐Lin, Chen, Yu‐Fei, Meng, Hong‐Zheng, Du, Jun‐Jie, Luan, Guan‐Nan, Wang, Hai‐Qiang, Yang, Mao‐Wei, Luo, Zhuo‐Jing
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485035/
https://ncbi.nlm.nih.gov/pubmed/27227700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23313
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