SHP-2 Activating Mutation Promotes Malignant Biological Behaviors of Glioma Cells

BACKGROUND: This study investigated the mechanism underlying the activating mutation of SHP-2 in promoting malignant biological behaviors of glioma cells. MATERIAL/METHODS: The SHP-2 empty plasmid pcDNA3.1 and SHP-2 activating mutation plasmid pcDNA3.1 SHP-2 (D61G) mutant eukaryotic expression vecto...

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Udgivet i:Med Sci Monit
Main Authors: Zhao, Yong, Lin, Lin, Zhang, Yonghui, Geng, Dangmurenjiafu
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2017
Fag:
Lab/In Vitro Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484608/
https://ncbi.nlm.nih.gov/pubmed/28620155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.904381
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