Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements

The Gram-negative bacterium Proteus mirabilis is a leading cause of catheter-associated urinary tract infections (CAUTIs), which are often polymicrobial. Numerous prior studies have uncovered virulence factors for P. mirabilis pathogenicity in a murine model of ascending UTI, but little is known con...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Armbruster, Chelsie E., Forsyth-DeOrnellas, Valerie, Johnson, Alexandra O., Smith, Sara N., Zhao, Lili, Wu, Weisheng, Mobley, Harry L. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484520/
https://ncbi.nlm.nih.gov/pubmed/28614382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006434
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