Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus

We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern of the fetal serotonin transporter gene (SLC6A4), and examined the functional relevance of DNA methylation for regulation of the SLC6A4 expression in the human placenta. The study included 50 mother-...

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Publicat a:PLoS One
Autors principals: Blazevic, Sofia, Horvaticek, Marina, Kesic, Maja, Zill, Peter, Hranilovic, Dubravka, Ivanisevic, Marina, Desoye, Gernot, Stefulj, Jasminka
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484502/
https://ncbi.nlm.nih.gov/pubmed/28650965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179934
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