Identification of Cytomegalovirus-Specific Cytotoxic T Lymphocytes In Vitro Is Greatly Enhanced by the Use of Recombinant Virus Lacking the US2 to US11 Region or Modified Vaccinia Virus Ankara Expressing Individual Viral Genes

Cytomegalovirus (CMV) elicits a potent T-cell response in humans that appears to protect the host from virus-associated disease. Despite facing strong host defense mechanisms, CMV remains as a lifelong infection that may reactivate and cause life-threatening disease in immunocompromised individuals....

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Detalhes bibliográficos
Main Authors: Khan, Naeem, Bruton, Rachel, Taylor, Graham S., Cobbold, Mark, Jones, Thomas R., Rickinson, Alan B., Moss, Paul A. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548448/
https://ncbi.nlm.nih.gov/pubmed/15709006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.2869-2879.2005
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