Quasispecies Heterogeneity within the E1/E2 Region as a Pretreatment Variable during Pegylated Interferon Therapy of Chronic Hepatitis C Virus Infection

A series of 29 patients undergoing treatment for chronic hepatitis C virus (HCV) genotype 1 infection with pegylated alpha-2a interferon plus ribavirin were studied for patterns of response to antiviral therapy and viral quasispecies evolution. All patients were treatment naive and had chronic infla...

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Detalhes bibliográficos
Main Authors: Chambers, Thomas J., Fan, Xiaofeng, Droll, Deborah A., Hembrador, Edgardo, Slater, Tiffany, Nickells, Michael W., Dustin, Lynn B., DiBisceglie, Adrian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548442/
https://ncbi.nlm.nih.gov/pubmed/15709027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.5.3071-3083.2005
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