Detection of Emerging Vaccine-Related Polioviruses by Deep Sequencing

Oral poliovirus vaccine can mutate to regain neurovirulence. To date, evaluation of these mutations has been performed primarily on culture-enriched isolates by using conventional Sanger sequencing. We therefore developed a culture-independent, deep-sequencing method targeting the 5′ untranslated re...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Sahoo, Malaya K., Holubar, Marisa, Huang, ChunHong, Mohamed-Hadley, Alisha, Liu, Yuanyuan, Waggoner, Jesse J., Troy, Stephanie B., Garcia-Garcia, Lourdes, Ferreyra-Reyes, Leticia, Maldonado, Yvonne, Pinsky, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483918/
https://ncbi.nlm.nih.gov/pubmed/28468861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00144-17
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