Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis

BACKGROUND: The lipoprotein(a) pathway is a causal factor in coronary heart disease. We used a genetic approach to distinguish the relevance of two distinct components of this pathway, apolipoprotein(a) isoform size and circulating lipoprotein(a) concentration, to coronary heart disease. METHODS: In...

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Publicat a:Lancet Diabetes Endocrinol
Autors principals: Saleheen, Danish, Haycock, Philip C, Zhao, Wei, Rasheed, Asif, Taleb, Adam, Imran, Atif, Abbas, Shahid, Majeed, Faisal, Akhtar, Saba, Qamar, Nadeem, Zaman, Khan Shah, Yaqoob, Zia, Saghir, Tahir, Rizvi, Syed Nadeem Hasan, Memon, Anis, Mallick, Nadeem Hayyat, Ishaq, Mohammad, Rasheed, Syed Zahed, Memon, Fazal-ur-Rehman, Mahmood, Khalid, Ahmed, Naveeduddin, Frossard, Philippe, Tsimikas, Sotirios, Witztum, Joseph L, Marcovina, Santica, Sandhu, Manjinder, Rader, Daniel J, Danesh, John
Format: Artigo
Idioma:Inglês
Publicat: The Lancet, Diabetes & Endocrinology 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483508/
https://ncbi.nlm.nih.gov/pubmed/28408323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-8587(17)30088-8
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