Solid lipid nanoparticles delivering anti-inflammatory drugs to treat inflammatory bowel disease: Effects in an in vivo model

AIM: To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate. METHODS: Dexamethasone cholesteryl butyrate-solid lipid nanoparticles (DxCb-SLN) were obtained with the warm microemulsion method. The anti-inflammatory activity...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Dianzani, Chiara, Foglietta, Federica, Ferrara, Benedetta, Rosa, Arianna Carolina, Muntoni, Elisabetta, Gasco, Paolo, Della Pepa, Carlo, Canaparo, Roberto, Serpe, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2017
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483494/
https://ncbi.nlm.nih.gov/pubmed/28694660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i23.4200
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