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Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells

Human cytomegalovirus (HCMV) primary infection and periodic reactivation of latent virus is generally well controlled by T-cell responses in healthy people. In older donors, overt HCMV disease is not generally seen despite the association of HCMV infection with increased risk of mortality. However,...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Jackson, Sarah E., Sedikides, George X., Okecha, Georgina, Poole, Emma L., Sinclair, John H., Wills, Mark R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483450/
https://ncbi.nlm.nih.gov/pubmed/28694811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00733
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