ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions

The Twist1 transcription factor promotes tumor invasion and metastasis by inducing epithelial–mesenchymal transition (EMT) and invadopodia-mediated extracellular matrix (ECM) degradation. The critical transcription targets of Twist1 for mediating these events remain to be uncovered. Here, we report...

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Bibliografische gegevens
Gepubliceerd in:J Cell Sci
Hoofdauteurs: Eckert, Mark A., Santiago-Medina, Miguel, Lwin, Thinzar M., Kim, Jihoon, Courtneidge, Sara A., Yang, Jing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482979/
https://ncbi.nlm.nih.gov/pubmed/28468988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198200
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