Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain

BACKGROUND: All known biological functions of the pro-inflammatory cytokine interleukin-1β (IL-1β) are mediated by type 1 interleukin receptor (IL-1R1). IL-1β–IL-1R1 signaling modulates various neuronal functions including spinal pain processing. Although the role of IL-1β in pain processing is gene...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Holló, Krisztina, Ducza, László, Hegyi, Zoltán, Dócs, Klaudia, Hegedűs, Krisztina, Bakk, Erzsébet, Papp, Ildikó, Kis, Gréta, Mészár, Zoltán, Bardóczi, Zsuzsanna, Antal, Miklós
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482961/
https://ncbi.nlm.nih.gov/pubmed/28645297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0902-x
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