cAMP response element binding protein (CREB) activates transcription via two distinct genetic elements of the human glucose-6-phosphatase gene

BACKGROUND: The enzyme glucose-6-phosphatase catalyzes the dephosphorylation of glucose-6-phosphatase to glucose, the final step in the gluconeogenic and glycogenolytic pathways. Expression of the glucose-6-phosphatase gene is induced by glucocorticoids and elevated levels of intracellular cAMP. The...

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Bibliographic Details
Main Authors: Thiel, Gerald, Al Sarraj, Jude, Stefano, Luisa
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC548273/
https://ncbi.nlm.nih.gov/pubmed/15659240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-6-2
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