High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin

Polypyrimidine tract-binding protein 1 (PTBP1) involving in almost all steps of mRNA regulation including alternative splicing metabolism during tumorigenesis due to its RNA-binding activity. Initially, we found that high expressed PTBP1 and poor prognosis was interrelated in colorectal cancer (CRC)...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Wang, Zhi-na, Liu, Dan, Yin, Bin, Ju, Wen-yi, Qiu, Hui-zhong, Xiao, Yi, Chen, Yuan-jia, Peng, Xiao-zhong, Lu, Chong-mei
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482648/
https://ncbi.nlm.nih.gov/pubmed/28404950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15873
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