Glioma stem cells-derived exosomes promote the angiogenic ability of endothelial cells through miR-21/VEGF signal

Glioma stem cells (GSCs) play an important role in glioblastoma prognosis. Exosomes (EXs) mediate cell communication by delivering microRNAs (miRs). Glioblastoma has a high level of miR-21 which could upregulate vascular endothelial growth factor (VEGF) expression. We hypothesized GSC-EXs can promot...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Sun, Xu, Ma, Xiaotang, Wang, Jinju, Zhao, Yuhui, Wang, Yue, Bihl, Ji C., Chen, Yanfang, Jiang, Chuanlu
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482644/
https://ncbi.nlm.nih.gov/pubmed/28410224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16661
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