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Network-assisted target identification for haploinsufficiency and homozygous profiling screens
Chemical genomic screens have recently emerged as a systematic approach to drug discovery on a genome-wide scale. Drug target identification and elucidation of the mechanism of action (MoA) of hits from these noisy high-throughput screens remain difficult. Here, we present GIT (Genetic Interaction N...
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| Udgivet i: | PLoS Comput Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482495/ https://ncbi.nlm.nih.gov/pubmed/28574983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005553 |
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