O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α

PGC1α is a coactivator of many transcription factors and cytosolic phosphoenolpyruvate carboxykinase (PCK1) is a key enzyme for gluconeogenesis. PGC1α interacts with the transcription factor PPARγ to stimulate PCK1 expression and thus de novo glucose synthesis. These proteins are not only important...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Latorre, Pedro, Varona, Luis, Burgos, Carmen, Carrodeguas, José A., López-Buesa, Pascual
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482481/
https://ncbi.nlm.nih.gov/pubmed/28644880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179988
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