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Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci

A-type resistance towards “last-line” glycopeptide antibiotic vancomycin in the leading hospital acquired infectious agent, the enterococci, is the most common in the UK. Resistance is regulated by the VanR(A)S(A) two-component system, comprising the histidine sensor kinase VanS(A) and the partner r...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Hughes, C.S., Longo, E., Phillips-Jones, M.K., Hussain, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482315/
https://ncbi.nlm.nih.gov/pubmed/28511809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.05.011
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