MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to food-grade synthetic amorphous silica

BACKGROUND: Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition receptors such as Nod-like or Toll-like receptors (TLRs) to launch immune reactions against pathogens, but also to mediate tolerance to se...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Winkler, Hans Christian, Kornprobst, Julian, Wick, Peter, von Moos, Lea Maria, Trantakis, Ioannis, Schraner, Elisabeth Maria, Bathke, Barbara, Hochrein, Hubertus, Suter, Mark, Naegeli, Hanspeter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481969/
https://ncbi.nlm.nih.gov/pubmed/28645296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-017-0202-8
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