Extinction of Cocaine Seeking Requires a Window of Infralimbic Pyramidal Neuron Activity after Unreinforced Lever Presses

The infralimbic cortex (IL) mediates extinction learning and the active suppression of cocaine-seeking behavior. However, the precise temporal relationship among IL activity, lever pressing, and extinction learning is unclear. To address this issue, we used activity-guided optogenetics in male Sprag...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Gutman, Andrea L., Nett, Kelle E., Cosme, Caitlin V., Worth, Wensday R., Gupta, Subhash C., Wemmie, John A., LaLumiere, Ryan T.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481943/
https://ncbi.nlm.nih.gov/pubmed/28539416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3821-16.2017
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